e-Live Motivation: When the Adults Suffering from Depression

Market research for women, men and depression suggest an estimated 4.4 million Americans who suffer from chronic treatment-resistant depression. Depression is a chronic, disorder off and the main public health problem worldwide. Depressive episodes are usually repeated over time, the risk for further episodes proportionally to the number of previous episodes. After three major depressive episodes, the likelihood of repetition is 90%. Only in the United States, approximately 18 million people suffer from depression than six million, who receive some kind of treatment.

Market studies on women, men and depression and the evaluation of more than 100,000 Americans each year are treated with electro convulsive therapy (etc.) for depression. Approximately 15% of all people with severe depression, requiring hospitalization suicide. Disorders related to men and depression is very expensive. Depression was assessed as the second major cause of disability worldwide in 1990. Depression costs the U.S. alone is estimated to exceed 50 billion dollars annually, including more than 12 billion dollars in direct costs of treatment. The total market in the United States on anti-DEPRESSANTS is estimated to exceed 6 billion dollars.

Some general factors May be related to women, men and depression, but the exact cause of the depressive disorder is unknown, although both biological abnormalities and psychological factors are considered precipitate this disease. Reduce the synaptic concentration of neurotransmitters, particularly serotonin and noradrenalin, is involved in the pathogenesis of depression. Most of the current standard treatment in terms of man and thought that depression affects either one or both of these neurotransmitter systems (1) drugs SSRI (serotonin specific refund inhibitors) or (2) MAOI drugs (monoamine oxidase inhibitors), which reduce the breakdown of serotonin and norepinephrine . It is interesting that some antiepileptics compounds such as carbamazepine, valproate and lamotrigine, are used as mood stabilizers, and that lamotrigine and gabapentin are also used as antidepressants.